活性成分
离解常数
酸离解常数
化学
离解(化学)
生化工程
有机化学
水溶液
药理学
医学
生物化学
工程类
受体
作者
Sandra Babić,Alka J.M. Horvat,Dragana Mutavdžić Pavlović,Marija Kaštelan‐Macan
标识
DOI:10.1016/j.trac.2007.09.004
摘要
The acid dissociation constant is an important physicochemical parameter of a substance, and knowledge of it is of fundamental importance in a wide range of applications and research areas. We present a critical review of published methods and approaches for the determination of acid dissociation constants, with a special emphasis on the pKa values of active pharmaceutical ingredients.
科研通智能强力驱动
Strongly Powered by AbleSci AI