One-Step Synthesis of Nitriles from Acids, Esters and Amides Using DIBAL-H and Ammonium Chloride
化学
试剂
氯化铵
铵
氯化物
有机化学
药物化学
作者
Agnieszka Wojtkielewicz,Zenon Łotowski,Jacek W. Morzycki
出处
期刊：Synlett [Thieme Medical Publishers (Germany)] 日期：2015-09-03卷期号：26 (16): 2288-2292被引量：10
标识
DOI：10.1055/s-0034-1381060
摘要
A convenient, one-step procedure is presented for the conversion of carboxylic acids or their derivatives (esters, lactones, amides) to nitriles with an aminoalane reagent prepared from diisobutylaluminum hydride (DIBAL-H) and ammonium chloride.
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