Nutrigenetyka i nutrigenomika a leczenie otyłości i chorób towarzyszących

Nutrients have the ability to interact and modulate molecular mechanisms underlying an organism’s physiological functions. On the other hand, genetic makeup of an individual (genetic polymorphisms) coordinates their metabolic response to different nutrients and diets. Nutrigenomics and nutrigenetics elucidate the interaction between diet and genes, provide powerful approaches to unravel the complex relationship between nutritional molecules, genetic polymorphisms, and the biological system as a whole. Personalization of diet, based on assumptions of nutrigenetics/nutrigenomics, can help in optimize health and can be useful in treatment of obesity and many other metabolic disorders. Knowledge of being carrier of some alleles that can increase the risk of metabolic disorders especially could be used in prevention of many lifestyle diseases. (Forum Zaburzen Metabolicznych 2010, vol. 1, no 3, 156–167)