Recent advances on microRNA and bronchopulmonary dysplasia

Bronchopulmonary dysplasia(BPD) is a chronic lung disease of premature neonates characterized by arrested pulmonary alveolar development.There is increasing evidence that microRNAs(miRNA) regulate translation of messenger RNAs during lung organogenesis.The potential role of miRNAs in the pathogenesis of BPD is unclear.The miRNA generation, physiological function, the relationship between miRNA and BPD were reviewed in this article. Key words: miRNA; Bronchopulmonary dysplasia; Gene; Premature