Objective:To study clinical features of mycoplasma pneumoniae associated with nephritis and nephrotic syndrome in child ren. Methods :To view all children with acute nephritis(devi ded into three groups:post streptococcal glomerulonephritis,mycoplasma pneumonia e associated with glomerulonephritis and others) and nephrotic syndrome(mycoplas ma pneumoniae associated and primary),to analyse their clinical features. Results:Of all the objects,18.6% and 35% were mycoplasma pneumonia e associated with nephritis and nephrotic syndrome,which presented acute nephri tis syndrome and nephrotic syndrome.There were no significant difference between the three groups of nephritis on the frequence and the length of edema, high bl ood pressure and hematuria.But there was significant difference between the two groups of nephrotic syndrome on the age, sex, the length of edema and proteinuri a. Conclusiuon:Mycoplasma pneumoniae associated with nephriti s and nephrotic syndrome are the main cause of nephritis and nephrotic syndrome in children in the zone, which should be taken more attention. [