Magnetic polymer microspheres have been new biopolymer materials with great advantages in bioseperating engineering,biomedicine engineering,as it has not only polymer functional groups,but also magnetic characteristics.Polystyrene-acrylic acid Copolymerization Magnetic Microspheres were synthesized by dispersion polymerization and Fe_3O_4 as cores and Polystyrene-acrylic acid copolymers as shells.The microspheres were characterized by SEM and size analysis,molecular weight and solid content measurement all indicate that microspheres are small in size,narrow in distribution,stable in chemistry construction and rich in functional groups on their surface,all of which increase the polarity of microspheres.