Gastrointestinal Mucosal Barrier:Effects of Stress and Intervention

Stress can damage tight junction integrity and gastrointestinal mucosal barrier,cause gastrointestinal mucosal barrier dysfunction,and increase the gastrointestinal tract permeability,which ultimately cause the body to produce the inflammatory response.Its intervention can reduce the impact of stress on gastrointestinal permeability.The compositions and functions of gastrointestinal barrier,assessing of gastrointestinal barrier function and measuring of gastrointestinal permeability,and effects of stress on gastrointestinal mucosal barrier and intervention were reviewed in this paper,in order to provide reference for relieving the effects of stress on gastrointestinal mucosal barrier function.