微核
弓形虫
细胞器
生物
滑翔运动
原生动物寄生虫
微生物学
发病机制
运动性
细胞生物学
寄生虫寄主
免疫学
顶复亚门
抗体
疟疾
原生动物疾病
万维网
计算机科学
作者
Jinjin Zhu,Yan Wang,Yuanyuan Cao,Jilong Shen,Li Yu
标识
DOI:10.3389/fmicb.2021.666506
摘要
Toxoplasma gondii microneme is a specialized secretory organelle that discharges its contents at the apical tip of this apicomplexan parasite in a sequential and regulated manner. Increasing number of studies on microneme proteins (MICs) have shown them as a predominant and important role in host cell attachment, invasion, motility and pathogenesis. In this review, we summarize the research advances in one of the most important MICs complexes, TgMIC1/4/6, which will contribute to improve the understanding of the molecular mechanism of T. gondii infection and provide a theoretical basis for the effective control against T. gondii.
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