Application and prospect of multiomics techniques in susceptibility to occupational noise hearing loss

With the continuous innovation of technology, genomics and other omics techniques, such as transcriptomics, proteomics, and metabolomics, are increasingly becoming an important basis for precision medicine. Current research on susceptibility to occupational noise hearing loss (ONHL) has focused on genomics. Building the future of precision medicine is the focus of current ONHL research. Compared to single-omics studies, the use of multi-omics analysis can provide an integrated flow of information on ONHL susceptibility. This paper outlines the advantages and limitations of different histological techniques and the application of each histology in the disease, and focuses on the feasibility of applying multi-omics techniques in ONHL susceptibility research. The analysis of multi-omics techniques can better guide the comprehensive understanding of the disease in clinical research.