Mechanisms underlying the protective effects of San‐Bai decoction against UV radiation on the skin

USBT2627 suppresses melanin accumulation in vitro and protects skin against UV exposure in both in vitro and in vivo models; multiple components, targets and pathways of SBD act together to confer its protective effect against UV exposure. These findings highlight a significant potential of topical USBT2627 in protecting skin against UV exposure. Additionally, this study showcases the value of a systems network approach in elucidating the mechanisms of this herbal blend, offering valuable references for further research aimed at developing TCM-based products.