高强度
人类免疫缺陷病毒(HIV)
白质
医学
内科学
磁共振成像
心理学
病毒学
放射科
作者
Kathryn B. Holroyd,Phillip Chan,Carlo Sacdalan,Netsiri Dumrongpisutikul,Somchai Sriplienchan,Pathariya Promensa,Pom Sailasuta,Mantana Pothisri,Suwanna Puttamaswin,Sandhya Vasan,Victor Valcour,Lydie Trautmann,Serena Spudich,Robert Paul,Jacob Bolenzius,as the RV254/SEARCH 010 Study Team
出处
期刊:Neurology
[Lippincott Williams & Wilkins]
日期:2025-05-06
卷期号:104 (10): e213591-e213591
被引量:2
标识
DOI:10.1212/wnl.0000000000213591
摘要
Young Thai men with AHI demonstrated greater WMH progression than PWoH over 2 years despite ART initiation and viral suppression. These data suggest that brain white matter is vulnerable to HIV during early infection, independent from vascular comorbidities or lifestyle factors. Limitations include homogeneity in sex and ethnicity and follow-up period limited to 24 months.
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