Continuous Photocatalytic C-C coupling Reaction by Palladium Single-Atom Anchored Covalent Organic Framework

We firstly reported a single-atom palladium photocatalyst, Pd-Ace-COF, for a continuous C-C coupling reaction. Under visible light irradiation, Pd-Ace-COF efficiently drives C-C coupling to form biphenyl with a >99% yield. Impressively, Pd-Ace-COF exhibits good stability and high activity in the continuous-flow reactor, highlighting its great potential for practical applications.