血管平滑肌
钙化
棕榈酸
细胞凋亡
内科学
医学
内分泌学
下调和上调
骨形态发生蛋白2
脂肪酸
生物
生物化学
平滑肌
基因
体外
作者
Yafen Tao,Yue Wu,Chuanyue Jiang,Qiang-Hua Wang,Xu Geng,Lei Chen,Sihui Zhou,Xuegu Wang,Mingliang Han,Danli Du,Biao Ding,Xiang Li
标识
DOI:10.1097/hjh.0000000000003342
摘要
This study demonstrated that vascular calcification induced by HFD was linked to the palmitic acid-induced downregulation of SIRT6. Overexpression of SIRT6 could decrease palmitic acid-induced calcification and apoptosis in VSMCs.
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