Direct laser marking techniques are widely used for various applications. Laser marking method has technical issues for full-color marking due to its printing principles. We have conducted the study of condition for single magenta and cyan developing in the direct color marking method which selectively develops three color layers by direct laser irradiation to thermo-sensitive recording paper. We tried to estimate duration time for heating by thermal transfer simulation with one-dimensional model and conducted study of condition of laser irradiation based on a result of thermal transfer simulation As a result of the condition study, we revealed that non-contact direct single magenta and cyan color marking with laser was possible using our method. In this paper, we report on process to develop single magenta and cyan by laser irradiation.