喹啉
荧光
检出限
硫化氢
化学
斯托克斯位移
光化学
分子
硫黄
有机化学
色谱法
量子力学
物理
作者
Fengting Liu,Wen-Wen Han,Hui Ren,Wan-Jing Yang,Ruonan Wang,Miao Jiang,Bao‐Xiang Zhao,Zhao‐Min Lin
标识
DOI:10.1016/j.dyepig.2022.111017
摘要
Similar to nitric oxide (NO) molecule, carbon monoxide (CO) molecule and hydrogen sulfide (H2S) molecule, sulfur dioxide (SO2) is also considered to be another important endogenous signaling molecule. SO2 derivatives are widely used as food antioxidants and antimicrobial agents. However, SO2 is also a toxic environmental pollutant and intake of elevated levels of sulfites can lead to diarrhea, low blood pressure and allergic and asthmatic reactions in susceptible people. The specific physiological effects and transformation processes of SO2 and its derivatives are not well understood due to the limitations of existing detection methods. Therefore, it is an urgent need to develop highly sensitive, high-resolution, real-time in situ assays. Herein, we specifically designed a ratiometric near-infrared fluorescent probe CQT for detecting SO2 derivatives. After the reaction of CQT with HSO3−/SO32−, a gradual decrease in red fluorescence at 662 nm accompanied by an enhanced blue fluorescence at 489 nm, reaching a detection range of 2.8–80 μM. In addition, we found that CQT had high energy transfer efficiency, large Stokes shift and low detection limit, which meant that CQT could sensitively monitor small changes of SO2 concentration in cells and accurately target lysosomes.
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