铁质
脂质过氧化
细胞内
癌细胞
活性氧
化学
新陈代谢
细胞
癌症研究
癌症
GPX4
细胞生物学
生物化学
生物
氧化应激
超氧化物歧化酶
有机化学
谷胱甘肽过氧化物酶
遗传学
作者
Shenghang Wang,Jie Luo,Zhihao Zhang,Dandan Dong,Ying Shen,Yanwen Fang,Lijiang Hu,Mengyu Liu,Chengfu Dai,Songlin Peng,Zhicai Fang,Peng Shang
出处
期刊:PubMed
[National Institutes of Health]
日期:2018-01-01
卷期号:8 (10): 1933-1946
被引量:118
摘要
) in acidic lysosomes and inducing ferroptosis. Magnetic field is widely used in the targeted concentration of iron-based NPs related disease therapy. Furthermore, multiple studies showed that magnetic fields can inhibit cancer cell proliferation by promoting intracellular ROS production. Herein, we focus on the relationship of between ferroptosis and iron metabolism in cancer cells, the application of nanoparticles and magnetic field in inducing ferroptosis of cancer cells, and trying to provide new ideas for cancer treatment research.
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