Efficacy of Shegan Mahuang Decoction for asthma

Abstract Background: Shegan Mahuang Decoction (SMD) was used widely for treatment of asthma in China; however, the clinical effect of SMD on asthma was not well concluded. Methods: Seven electronic databases (Medline, Cochrane library, EMBASE database, Chinese National Knowledge Infrastructure, Wanfang database, Chongqing VIP database, and Chinese Biomedicine database) will be searched for randomized controlled trials which meet the eligible criteria. Two reviewers will select studies and extract data independently. Risk of bias will be evaluated using modified Jadad score. Data synthesis will be carried out using RevMan 5.3. Sensitivity analysis and publication bias will also be investigated. Results: This systematic review and meta-analysis will review and synthesis current clinical evidence of SMD for the treatment of asthma. Conclusion: This systematic review and meta-analysis will provide high quality evidence of SMD for the treatment of asthma. Registration: PROSPERO CRD42019141810.