Clinical research progress in prostate cancer gene 3

Prostate cancer is one of the common malignant tumor of elderly men,there is still no satisfactory method for the differential diagnosis,disease progression and prognostic judgment of prostate cancer.In recent years,prostate cancer gene 3(PCA3) may be the most promising specific markers for prostate cancer in clinical studies,its predictive effect has been confirmed widely in biopsy,it can help to improve prostate cancer diagnosed rate in conjunction with other diagnostic methods and is expected to have special role in predicting tumor aggressiveness and gene therapy.This essay summarizes the research on prediction function in the first time,repeat biopsy of PCA3,PCA3 score's relationship with prostate volume and Gleason grade,PCA3's prediction in the effect of prostate cancer combined with other inspection method,targeted gene therapy effect.