Risk factors analysis and clinical significance of infection after orthopedic internal fixation

Objective To investigate the risk factors of the infection after orthopedic internal fixation,provide a reference for prevention of infection after orthopedic internal fixation.Methods 52 case of infection patients after internal fixation in our hospital from January 2004 to December 2010 were retrospectively collected,and at the same time,104 cases of no-infected in our department were collected.Univariate analysis on open or not,polluted or not,internal fixed material and other information were took.Multivariate analysis on significant related factors were took.Results Univariate analysis showed: open or not,wound polluted or not,multiple fractures or not,operation time,using of hormones,diabetes and merger basic disease were significantly associated with infections after orthopedic internal fixation.Multivariate analysis showed: wound polluted or not,multiple fractures or not,operation time,using of hormones,diabetes and merger basic disease were independent risk factor of the after orthopedic internal fixation.Conclusion Treatment of infection after orthopedic internal fixation is difficult.Paying attention to the reference value of these risk factors in infection after the internal fixation may further reduce the occurrence of infection after the internal fixation.