Clinical Curative Effect Investigation of Lingzhi Tablets on Lung Cancer

Objective: To study the clinical effects of Lingzhi Tablets (LZT) cultivated in Japan on patients suffering from lung cancers. Methods: 29 patients diagnosed as Ⅲ～Ⅳ stage lung cancers were randomly divided into LZT treated group and control group. The effects of LZT on immune regulation, hemorheologic parameters and clinical manifestations were observed. Results: It was observed that the level of Tumor Necrosis Factor (TNF) was raised obviously from 17.7±4.3 to 28.7±6.6 pg/ml in LZT group. With the progression of the disease, the level of soluble interlleukin 2 acceptor (sIL 2R) was increased in control group, but kept stable in LZT group. Some hemorheologic parameters were decreased in LZT group. Although LZT had not been proved to reduce the lesion directly, it was helpful to improve the whole body state. No severe adverse reactions such as liver and kidney functions injuries happened in usual dose.Conclusion: LZT could regulate the immunity and improve the hypercoagulative condition.