Pathological analysis about liver tumor size measured with contrast enhanced ultrosonography compared with baseline ultrosonography and CT

【Objective】 To investigate accuracy of measurement of liver tumor size with contrast enhanced ultrasonography(CEUS) and to evaluate local infiltration of liver tumor judged with CEUS.【Methods】 54 patients with 61 liver tumors underwent baseline ultrasonography,contrast enhanced CT(CECT) and CEUS before hepatoectomy.The tumor size was measured with baseline ultrasonography,CECT and CEUS at the largest section and then compared with the resected gross and microscopic findings.The infiltration depth of the malignancies,the pathological character of the tumor and tissues surrounding the tumor were analyzed.【Results】 There was no significant difference among liver tumor sizes measured on Baseline ultrasonography,CECT and CEUS,with better correlation with the size of the resected gross specimen(r =0.904,0.901,0.894 respectively).Of them,the size on CEUS was larger than the size on the resected gross specimen,which mean difference was 0.35 cm.the sizes on baseline ultrasonography and CECT were smaller than the size on the resected gross specimen,which mean difference was 0.06 cm and 0.08 cm respectively.There was significant difference in terms of the infiltration depth of the malignancies between lesions with the larger size on CEUS than that on baseline ultrasonography and the others with the same size on CEUS and on baseline ultrasonography(P 0.05).【Conclusions】 Baseline ultrasonography,CECT and CEUS can accurately measure the size of liver tumor.The contrast enhanced area on CEUS can accurately reflect the area of infiltrative malignancies.