Graft material for repair of peripheral nerve

Peripheral nerve lesions with a long segment defect need a grafting conduit to repair. Autogenous nerve grafts is still considered the best material for bridging nerve defects, but it is accompanied by some disadvantages, including insufficient graft material for the reconstruction of a large mixed nerve and complications setting in the site of donor. The results of this research demonstrate that the nerve grafting can be completed by using different bridging material. These peripheral nerve bridges as vehicle for moderation and modulation of the cellular and molecular ambience for nerve regeneration have different effects on the repair for peripheral nerve injury.