Early changes and clinical significances of C-reactive protein and high sensitive C-reactive protein in septicemia of newborn

Objective To appraise the early changes and clinical significances of C-reactive protein(CRP) and high sensitive C-reactive protein(hsCRP) in septicemia of newborn.Methods The densities of CRP and hsCRP were measured in 96 newborn patients with septicemia(septicaemia group) and 93 newborn patients with other diseases(control group) from August 2009 to January 2011,then the changes of the CRP and hsCRP positive rate were observed in two groups.Results The CRP positive rate was 94.79% in septicaemia group,and 8.60% in control group,with the significant difference between them(P0.05);the hsCRP positive rate was 97.92% in septicaemia group,and 5.38% in control group,with the significant difference between them(P0.05).However,the densities of CRP and hsCRP were federatively measured can improve the successful rate.Conclusion The early changes of CRP and hsCRP were significant and they conduce to early clinical diagnosis in septicemia of newborn.