Multivariate analysis of risk factors for early postoperative hypoxemia following pulmonary resection

Objective To evaluate the risk factors of early postoperative hypoxemia after pulmonary resection and to analyze impacts of risk factors on hospitalization time and short-term mortality. Methods 262 postoperative patients admited in ICU in 2006 were investigated retrospectively. Patients with PaO2/FiO2 below 300mmHg detected on the next day after operation were diagnosed as early postoperative hypoxemia following pulmonary resection. Risk factors were analyzed and hospitalization time and short-term mortality were compared between hypoxemia group and non-hypoxemia group. Results Among the 262 cases 112(42.7%) were diagnosed as hypoxemia. Logistic regression analysis showed that age,operation range and anesthesia time were associated with early postoperative hypoxemia following pulmonary resection. There was significant difference between hypoxemia and non-hypoxemia group with regard to hospitalization time and no difference with short-term mortality. Conclusions Patients with age older than 65,larger operation range and longer anesthesia time have a higher risk for hypoxemia after pulmonary resection. Early hypoxemia does not show obvious negative impact on short-term mortality of patients. Early postoperative treatment in ICU maybe one of contributions to reduce short-term mortality.