Lipase-catalyzed synthesis of L-ascorbyl fatty acid esters and D-isoascorbyl fatty acid esters

The lipase-catalyzed synthesis of L-ascorbyl fatty acid esters and D-isoascorbyl fatty acid esters were studied by direct esterification and transesterification,respectively.The structures of products were confirmed by IR,1H NMR,13C NMR and MS.It was found that the yield of the direct esterification were higher than that of the corresponding transesterification under the similar synthetic conditions.The raw material fatty acids and fatty acid methyl esters could be recycled and reused.