Separation and abstracting process is one of the key steps during investigation of marine biomaterials.The kinds of the marine biomaterials are various,but their contents are very low.There are a lot of separation and abstracting technologies,such as precipitation,crystallization,adsorption,extraction,membrane separation ion-exchange and so on.Membrane separation technology has attracted great attention due to its advantages such as simple equipment,room temperature operation,non-phase change,high selectivity and low energy cost.The concentration,separation and purification of biomaterials could be achieved by using this technology through choosing proper membrane,process parameters and mode.As membrane separation technology is especially suitable for the treatment of both thermosensitive materials and biomaterials,it has a very capacious application perspective for the separation and abstracting of effective contents in marine biomaterials.The recent application advancement of membrane separation technology in separation and purification of the marine biomaterials is introduced in detail in this paper.