5-Fluorouracil,Leucovorin and Carmofur Combination in Treatment for Advanced Large-intestinal Cancer

To investigate the effect of combination of 5 fluorouracil,leucovorin and carmofur or 5 fluorouracil and leucovorin in treatment for advanced large intestinal cancer.From October 1998 to April 2000,36 cases who suffered from advanced large intestinal cancer were divided into two groups randomly,the treatment group with 5 fluorouracil,leucovorin and carmofur combination;control group with 5 fluorouracil and leucovorin.The overall response rates was 55.5% in treatment group and 27.7% in control group.[Conclusion]5 fluorouracil,leucovorin and carmofur combination is more effective than 5 fluorouracil and leucovorin combination for advanced large intestinal cancer.