Aldehyde Oxidase: An Enzyme of Emerging Importance in Drug Discovery

ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTAldehyde Oxidase: An Enzyme of Emerging Importance in Drug DiscoveryDavid C. Pryde*†, Deepak Dalvie‡, Qiyue Hu§, Peter Jones†, R. Scott Obach∥, and Thien-Duc Tran†View Author Information† WorldWide Medicinal Chemistry, Pfizer Global Research and Development, Sandwich, Kent, CT13 9NJ, England‡ Pharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development, 10628 Science Center Drive, La Jolla, California 92121§ WorldWide Medicinal Chemistry, Pfizer Global Research and Development, 10628 Science Center Drive, La Jolla, California 92121∥ Pharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development, Eastern Point Road, Groton, Connecticut 06340*To whom correspondence should be addressed. Phone: +44 (1304) 643687. Fax: +44 (0) 1304 651987. E-mail: [email protected]Cite this: J. Med. Chem. 2010, 53, 24, 8441–8460Publication Date (Web):September 20, 2010Publication History Received15 July 2010Published online20 September 2010Published inissue 23 December 2010https://pubs.acs.org/doi/10.1021/jm100888dhttps://doi.org/10.1021/jm100888dreview-articleACS PublicationsCopyright © 2010 American Chemical SocietyRequest reuse permissionsArticle Views12272Altmetric-Citations286LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Anatomy,Metabolism,Oxidation,Peptides and proteins,Rodent models Get e-Alerts