Research Progress of the Effect of Berberine on the Metabolism of Glucose and Lipids

Berberine has been reported to modulate glucose and lipid metabolism in the body.This review was renewed its reported beneficial effect in insulin secretion and insulin signaling pathway,glucose transport and metabolism,low density lipoprotein receptor,AMP kinase activity,adipocytes differentiation,lipid and energy metabolism,and attempted to discuss the mechanisms of berberine in regulating glucose and lipid metabolism and its joint regulation,which indicated the clinical application prospects and problems of berberine.