Ultrasonic enhanced Fenton agent is used for desulfurization of dibenzothiophene,a target for diesel oil, by catalytic oxidation method. The reaction is carried out under the following conditions: 40℃ of reaction temperature, 2. 1 of pH,0. 08 mass ratio of Fe2 +and H2O2and 25 kHz of ultrasonic frequency. The desulfurization rate is increased by 36% when the reaction time and ultrasonic frequency are 10 minutes and 150 W,respectively,comparing with the samples without ultrasonic treatment. It indicates that ultrasonic treatment obviously promotes the desulfurization of dibenzothiophene.