canSAR: update to the cancer translational research and drug discovery knowledgebase
作者
Elizabeth A. Coker,Costas Mitsopoulos,Joesph E. Tym,Angeliki Komianou,Christos Kannas,Patrizio Di Micco,Eloy Villasclaras Fernandez,Buğra Özer,Albert A. Antolín,Paul Workman,Bissan Al‐Lazikani
出处
期刊:Nucleic Acids Research [Oxford University Press] 日期:2018-11-26卷期号:47 (D1): D917-D922被引量:124
canSAR (http://cansar.icr.ac.uk) is a public, freely available, integrative translational research and drug discovery knowlegebase. canSAR informs researchers to help solve key bottlenecks in cancer translation and drug discovery. It integrates genomic, protein, pharmacological, drug and chemical data with structural biology, protein networks and unique, comprehensive and orthogonal 'druggability' assessments. canSAR is widely used internationally by academia and industry. Here we describe major enhancements to canSAR including new and expanded data. We also describe the first components of canSARblack-an advanced, responsive, multi-device compatible redesign of canSAR with a question-led interface.