生育率
受体
生物
内分泌学
内科学
医学
遗传学
环境卫生
人口
作者
Emilie Brûlé,Ying Wang,Yining Li,Yeu‐Farn Lin,Xiang Zhou,Luisina Ongaro,Carlos Agustín Isidro Alonso,Evan R. S. Buddle,Alan L. Schneyer,Chang‐Hyeock Byeon,Cynthia S. Hinck,Natalia Mendelev,John P. Russell,Mitra Cowan,Ulrich Boehm,Frederique Ruf-Zamojski,Michel Zamojski,Cynthia L. Andoniadou,Stuart C. Sealfon,Craig A. Harrison
出处
期刊:Science Advances
[American Association for the Advancement of Science]
日期:2021-12-15
卷期号:7 (51): eabl4391-eabl4391
被引量:37
标识
DOI:10.1126/sciadv.abl4391
摘要
knockout mice exhibit increased FSH levels, ovarian follicle development, and litter sizes. In contrast, female mice lacking both TGFBR3L and betaglycan are infertile. TGFBR3L’s function and cell-specific expression make it an attractive new target for the regulation of FSH and fertility.
科研通智能强力驱动
Strongly Powered by AbleSci AI