髓系白血病
多发性骨髓瘤
癌症研究
核糖核酸
医学
生物
肿瘤科
内科学
基因
遗传学
出处
期刊:Cancer Discovery
[American Association for Cancer Research]
日期:2014-10-10
卷期号:4 (12): OF5-OF5
被引量:4
标识
DOI:10.1158/2159-8290.cd-nb2014-154
摘要
Abstract In a preclinical study, the investigational drug CX-5461, which blocks the protein RNA polymerase I, extended survival in mouse models of highly aggressive acute myeloid leukemia and multiple myeloma refractory to standard therapy.
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