Direct Synthetic Approach to N Aminoimidazole2thiones and Imidazole Derivatives

In an efficient one-pot/multi-step procedure 1-anilino-2,3-dihydro-1H-imidazole-2-thiones were prepared starting from ±-haloketones. The structure of the imidazole-2-thiones were studied with NMR techniques. Further reactions were performed using the imidazole-2-thiones as starting material.