脂肪生成
脂肪细胞
转录因子
生物
细胞生物学
脂肪组织
Mef2
信号通路
细胞分化
信号转导
间充质干细胞
遗传学
增强子
内分泌学
基因
作者
Evan D. Rosen,Ormond A. MacDougald
摘要
Improved knowledge of all aspects of adipose biology will be required to counter the burgeoning epidemic of obesity. Interest in adipogenesis has increased markedly over the past few years with emphasis on the intersection between extracellular signals and the transcriptional cascade that regulates adipocyte differentiation. Many different events contribute to the commitment of a mesenchymal stem cell to the adipocyte lineage including the coordination of a complex network of transcription factors, cofactors and signalling intermediates from numerous pathways.
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