脱落酸
生物
受体
磷酸酶
磷酸化
非生物胁迫
生物化学
非生物成分
细胞生物学
基因
生态学
作者
Julia Santiago,Florine Dupeux,Katja Betz,Regina Antoni,Miguel González-Guzmán,Lesia Rodriguez,José Antonio Márquez,Pedro L. Rodriguez
出处
期刊:Plant Science
[Elsevier]
日期:2012-01-01
卷期号:182: 3-11
被引量:93
标识
DOI:10.1016/j.plantsci.2010.11.014
摘要
Abscisic acid (ABA) plays an essential function in plant physiology since it is required for biotic and abiotic stress responses as well as control of plant growth and development. A new family of soluble ABA receptors, named PYR/PYL/RCAR, has emerged as ABA sensors able to inhibit the activity of specific protein phosphatases type-2C (PP2Cs) in an ABA-dependent manner. The structural and functional mechanism by which ABA is perceived by these receptors and consequently leads to inhibition of the PP2Cs has been recently elucidated. The module PYR/PYL/RCAR-ABA-PP2C offers an elegant and unprecedented mechanism to control phosphorylation signaling cascades in a ligand-dependent manner. The knowledge of their three-dimensional structures paves the way to the design of ABA agonists able to modulate the plant stress response.
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