Asymmetric construction of 2,6-methanobenzo[ g ][1,3]oxazocine scaffolds

An organocatalyzed strategy was established to enable the facile construction of 2,6-methanobenzo[ g ][1,3]oxazocine scaffolds from readily available o -hydroxy cinnamaldehydes and 3-aminoacrylates with high diastereoselectivity and enantioselectivity.