抗辐射性
肿瘤微环境
癌症研究
DNA损伤
免疫抑制
癌细胞
生物
放射治疗
癌症
材料科学
免疫学
医学
DNA
肿瘤细胞
内科学
遗传学
作者
Ruru Zhang,Mei Chen,Hui Zhou,Yan Liu,Yi Wang,Can Chen,Yueping Li,Jianfeng Zeng,Jiabin Cui,Ruixue Duan,Mingyuan Gao
标识
DOI:10.1002/adma.202406378
摘要
T cell infiltration of tumors, suppresses intratumoral myeloid-derived suppressor cells, and limits the M2 macrophages polarization, indicating the formation of an immunoreactive microenvironment. Significantly, this approach impedes the growth of not just primary, but also distal metastatic tumors. It is thus believed that the current ion generator provides a robust and enduring countermeasure to radioresistant cancer and its metastasis, with potential implications for enhancing the efficacy of RT in clinically resistant tumors.
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