Anaphylaxis has shown a steadily rising incidence in recent years, but remains under-reported, under-diagnosed and under-treated in China. To improve the diagnosis and management of anaphylaxis, this consensus elaborates on the pathogenesis, triggers, risk factors, clinical manifestations, diagnosis, treatment and prevention of anaphylaxis based on previously published evidence-based guidelines and practice parameters. Additionally, it proposes recommendations for the diagnosis and management of anaphylaxis specially for Chinese patients. This consensus aims to guide physicians in standardizing the management of anaphylaxis and to provide a framework for the development of new guidelines.