列线图
医学
癌症
内科学
比例危险模型
化疗
辅助化疗
多元分析
肿瘤科
回顾性队列研究
外科
乳腺癌
作者
Hua‐Long Zheng,Junqing Lin,Lili Song,Hai‐Bo Yang,Binbin Xu,Xue Zhang,Dong Wu,Jinxiong Huang,Guo Lin,Chao‐Hui Zheng,Ping Li,Jian-Wei Xie,Jia-Bin Wang,Lin Ji,Qi‐Yue Chen,Long‐Long Cao,Jun Lü,Chang‐Ming Huang
出处
期刊:Ejso
[Elsevier]
日期:2023-05-01
卷期号:49 (5): 964-973
被引量:1
标识
DOI:10.1016/j.ejso.2023.01.009
摘要
Background The Global Leadership Initiative on Malnutrition released a new version of the malnutrition criteria (GLIM criteria). To investigate the influence of the GLIM criteria on the long-term efficacy of radical gastric cancer surgery and establish a nomogram to predict the long-term prognosis of patients with gastric cancer. Methods A retrospective analysis of 1121 patients with gastric cancer in our department from 2010 to 2013 was performed. A nomogram was established to predict overall survival (OS) based on the GLIM criteria. Patients were divided into the low-risk group (LRG) and high-risk group (HRG) based on the established nomogram. Results Multivariate Cox regression analyses showed that GLIM criteria was an independent risk factor for the 5-year OS (HR = 1.768, Cl:1.341–2.329, p < 0.001). The C index, AUC and Time-ROC of the nomogram were significantly better than that of GLIM criteria and traditional criteria. The 5-year OS of patients receiving adjuvant chemotherapy in the high-risk group was significantly higher than that of patients without chemotherapy (45.77% vs. 24.73%,p < 0.001). Conclusions The GLIM criteria independently influence the long-term outcome of patients after radical gastric cancer surgery. The established nomogram can predict the long-term survival of patients with gastric cancer, and postoperative adjuvant chemotherapy for HRG can significantly improve the 5-year OS of patients.
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