吡啶
化学
碘
三嗪
试剂
药物化学
有机化学
吡啶类化合物
高分子化学
组合化学
作者
Zhiqi Liu,Yinghua Li,Weibin Fan,Deguang Huang
标识
DOI:10.1021/acs.joc.3c02517
摘要
An iodine-mediated method for the synthesis of 6-alkylthio-1,3,5-triazine-2,4-diamines by the reaction of N-alkylpyridinium salts and NH4SCN in air is reported. Twenty-seven compounds were obtained under the standard conditions. Pyridinium salts work as benzyl-group transfer reagents to promote the formation of the CBn–SSCN bond and thereby the construction of the triazine skeleton. A plausible mechanism is proposed based on the experimental results and literature survey.
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