血小板
药物输送
细胞外小泡
止血
药品
血管生成
富血小板纤维蛋白
细胞外
化学
小泡
药理学
医学
纤维蛋白
细胞生物学
生物
免疫学
癌症研究
生物化学
内科学
有机化学
膜
出处
期刊:Biomaterials Science
[The Royal Society of Chemistry]
日期:2023-01-01
卷期号:11 (17): 5758-5768
被引量:3
摘要
Platelet-derived extracellular vesicles (PEVs) are a subset of EVs that are released from platelets, which are small nuclear cell fragments that play a critical role in hemostasis and thrombosis. PEVs have been shown to have important roles in a variety of physiological and pathological processes, including inflammation, angiogenesis, and cancer. Recently, researchers, including our group have utilized PEVs as drug delivery platforms as PEVs could target inflammatory sites both passively and actively. This review summarizes the biological function of PEVs, introduces recent applications of PEVs in targeted drug delivery, and provides an outlook for the further development of utilizing PEVs for drug delivery.
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