Palladium-catalyzed cascade cyclization/intramolecular redox-relay Heck arylation of alkenols: access to tetrahydro-β-carbolines from 2-(hydroxyalkenynyl)sulfonanilides

The first palladium-catalyzed cascade reaction combining Pd( ii )-catalyzed nucleophilic cyclization of alkynes and intramolecular redox-relay Heck arylation of alkenols has been developed.