淋巴系统
免疫系统
肾
淋巴管内皮
化学
生物
免疫学
内分泌学
作者
Ashley Pitzer Mutchler,Jianyong Zhong,Haichun Yang,Shilin Zhao,Rachelle Crescenzi,Shannon L. Taylor,Rameshwar R. Rao,Elaine L. Shelton,Annet Kirabo,Valentina Kon
标识
DOI:10.1161/circresaha.124.324890
摘要
These findings reveal a novel mechanism linking the isolevuglandin-mediated ET-3/ETBR axis with LECs and infiltrating dendritic cells. ET-3/ETBR signaling in lymphatic vessel dynamics is a novel pathogenic component and a possible therapeutic target in kidney disease.
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