Unique Superbase TBD (1,5,7-Triazabicyclo[4.4.0]dec-5-ene): From Catalytic Activity and One-Pot Synthesis to Broader Application in Industrial Chemistry

TBD (1,5,7-triazabicyclo[4.4.0]dec-5-ene) is an organic superbase with unique catalytic effects due to its bifunctionality. It is already successfully used as a versatile catalyst, e.g., for transesterification, amidation, Michael addition, and aldol reactions, in technical silicone chemistry and even for enantioselective transformations. Currently, main applications are in innovative polymer chemistry (vitrimers, nonisocyanate polyurethanes, and polyureas). Restrictions of a broader application of TBD in technical processes due to its limited market availability and the complicated handling of its crystalline delivery form are now overcome by a simple one-pot synthesis of TBD, which generates an easy-to-make, ready-to-apply liquid formulation.