Zika Getting on Your Nerves? The Association with the Guillain–Barré Syndrome

Parra and colleagues1 report in the Journal the results of a prospective study of 68 Colombian patients who had a syndrome consistent with the Guillain–Barre syndrome, 66 of whom had previously had symptoms of Zika virus (ZIKV) infection. Major strengths of this study include the documentation of a temporal relationship between the Guillain–Barre syndrome and ZIKV infection (marked by a substantial increase in the incidence of the Guillain–Barre syndrome after the introduction of ZIKV, from 20 to 90 cases per month throughout Colombia), the criteria applied for the diagnosis of the Guillain–Barre syndrome, and the molecular and serologic flavivirus data . . .