医学
乙酰唑胺
中枢性睡眠呼吸暂停
睡眠呼吸暂停
肺动脉高压
呼吸暂停
心力衰竭
心脏病学
通风(建筑)
呼吸道疾病
内科学
呼吸
麻醉
阻塞性睡眠呼吸暂停
氧气疗法
多导睡眠图
肺
工程类
机械工程
作者
Robert Thurnheer,Silvia Ulrich,Konrad E. Bloch
摘要
Among patients with sleep apnea the reported prevalence of precapillary pulmonary hypertension (PH) has varied largely, depending on patient selection, disease definition, and associated conditions, in particular chronic pulmonary disease. However, in the absence of comorbidities, PH seems to be rare in patients with sleep apnea. Conversely, sleep-related breathing disorders have been commonly found in patients with PH and they have been associated with an impaired quality of life. Since sleep-related breathing disorders may affect the pulmonary circulation and vice versa, patients with sleep-related breathing disorders should be evaluated for risk factors, symptoms and clinical signs of PH and right ventricular heart failure and patients with PH should be evaluated for sleep apnea. Therapeutic options for patients with sleep apnea and PH may include supplemental oxygen, drugs and positive pressure ventilation. Both nocturnal oxygen administration and acetazolamide have been shown to improve sleep apnea in patients with PH. In addition, oxygen therapy also improved exercise performance. Further studies are needed to corroborate the efficacy of these and other treatments.
科研通智能强力驱动
Strongly Powered by AbleSci AI