Research Progress of the Inflammatory Mechanisms of Ischemic Stroke

Inflammatory mechanisms play a central role in the pathogenesis and progression of atherosclerosis,plaque rupture,thrombosis,and ischemic stroke.Multiple chronic exposures or infectious burden may contribute to atherosclerosisi and schemic stroke,acute infections have also been found to serve as stroke triggers.Inflammatory biomarkers such as high-sensitivity C-reactive protein have been identified as predictors of first stroke and prognosis after ischemic stroke.In addition to the traditional treatment of recombinant tissue plasminogen activator,statins,the current study of the drug include endothelin antagonists,drugs such as imatinib,are found to have the function of anti-inflammatory and anti-oxidation.