The collection of the municipal solid waste is an important link of the city environmental hygiene work. This paper analyses the output and the constitution of the municipal solid waste of Guangzhou City, according to this foundation, puts forward the category of the categorized collection of the municipal solid waste of Guangzhou City, points out the shortcomings of the present conditions of the municipal solid waste classification of Guangzhou City and the problem in the garbage recycling of Guangzhou City. Aiming at the problem the city is confronted, we make a preliminary investigation into the concrete suggestions of the categorized collection of the municipal solid waste. Adapting to the local conditions, this paper puts forward the integrated treatment of municipal solid waste handling route, and puts forward countermeasures for realizing the municipal solid waste reducing, recycling and innoxiousizing.