Angiotension-converting enzyme inhibitors(ACEI) and angiotension receptor antagonists,or angiotension receptor blockers(ARBs) are widely used in the treatment of cardiovascular disease.They play an important role in the prevention and treatment of cardiovascular disease.Many studies have shown that ACEI and ARBs have some effect in preventing arrhythmia,particularly in preventing atrial fibrillation.This article reviews the effects and mechanisms of ACEI and ARB in the prevention of arrhythmia.